donderdag 7 april 2016

Thyroxine products joint position statement

Weet je van wanneer deze verklaring is? Van 8 december 2004. En blijkbaar is het belang van deze verklaring nog steeds niet doorgedrongen in onze contreien. Substitutie van levothyroxine - met alle vervelende gevolgen - vindt nog steeds plaats.



Best Physician Practices


Patients should be maintained on the same brand name levothyroxine product. If the brand of levothyroxine medication is changed, either from one brand to another brand, from a brand to a generic product, or from a generic product to another generic product, patients should be retested by measuring serum TSH in six (6) weeks, and the drug reiterated as needed. Since small changes in levothyroxine administration can cause significant changes in TSH serum concentrations, precise and accurate TSH control is necessary to avoid potential adverse iatrogenic effects.

Best Patient Practices


Use the same brand of thyroid medication throughout your treatment. Thyroid disease often requires lifelong therapy and is best managed with consistent and precise treatment with the same brand of thyroid hormone. Your doctor may change your dose of thyroid hormone, but the brand of your thyroid hormone medication should always stay the same.

When you go to the pharmacy, do not change the brand of your thyroid medication without checking with your doctor. You should not change from one brand of thyroid medication to another, from your brand of thyroid medication to a generic product, or from one generic product to another without first checking with your doctor. Repeat blood tests and visits to your doctor may be required, and your dose may need to be readjusted if your thyroid medication is changed, or if you switch to a generic product.

Thyroid disease often requires lifelong therapy and is best managed with consistent and precise treatment. Do not change the brand of your thyroid medication without checking with your doctor. If the pharmacist suggests changing brands or recommends a generic product, you should also check with your doctor. Your insurance company or state aid program may not pay for the cost of a brand name drug or charge a higher co-payment if you want a specific brand name drug. Repeat blood tests and visits to your doctor may be required, and your dose may need to be readjusted if your thyroid medication is changed to a different brand, a generic product, or a different generic product.

References

  1. Hennessey JV. Levothyroxine a new drug? Since when? How could that be? Thyroid. 2003; 13,279-282
  2. Blakesley V, Awni W, Locke C, Ludden T, Granneman GR, Braverman LE. Are bioequivalence studies of levothyroxine sodium formulations in euthyroid volunteers reliable? Thyroid. 2004;14:191-200


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